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Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification − protocol for a cross-sectional, observational, diagnostic accuracy study

Abstract Introduction Yaws, caused by the bacterium Treponema pallidum subsp. pertenue, is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal. Diagnosis of yaws has relied heavily on clinical and serological tools. However, the presence of coendemic cutaneous skin ulcer diseases, such as lesions caused by […]

A Loop-Mediated Isothermal Amplification Assay for the Detection of Treponema pallidum subsp. pertenue

Abstract The eradication of yaws caused by Treponema pallidum subsp. pertenue is constrained by the lack of rapid, accurate diagnosis. We sought to develop a molecular point-of-care test for the diagnosis of yaws. A loop-mediated isothermal amplification (LAMP) assay with primers targeting the conserved gene, tp0967, with visual detection by lateral flow test strip was […]

Microfluidic rapid and autonomous analytical device (microRAAD) to detect HIV from whole blood samples

Abstract While identifying acute HIV infection is critical to providing prompt treatment to HIV-positive individuals and preventing transmission, existing laboratory-based testing methods are too complex to perform at the point of care. Specifically, molecular techniques can detect HIV RNA within 8–10 days of transmission but require laboratory infrastructure for cold-chain reagent storage and extensive sample […]

Incas Diagnostics Welcomes GardPath Technologies for a Collaborative Knowledge Exchange

Incas Diagnostics was delighted to recently host a visit from the team at Gardpath Technologies, a fellow Ghanaian organization dedicated to the development of diagnostic solutions, this time focusing on the animal health sector. The visit, highlighted by Gardpath Technologies on their LinkedIn page, saw their team engage with our CEO, Dr. Laud Anthony Basing, […]

Incas Diagnostics: Local Manufacturing of Low-Cost Diagnostic Products in Ghana

Listen to our discussion here ! Laud Anthony Basing, Founder and CEO of the Ghanaian biotech company Incas Diagnostics, was the guest on this episode of the Africa biotech conversations podcast. His company focuses on creating and manufacturing point-of-care lateral flow and molecular diagnostic tests designed specifically for Africa. In our inspiring and insightful conversation […]